Creatine ethyl ester, also known as creatine ester, cre-ester and CEE, is a creatine developed for athletic performance and for muscle development in the body. It is an ethyl ester derivative of creatine, from which it is made. As a supplement, the compound was developed, patented and licensed through UNeMed, the technology transfer entity of the University of Nebraska Medical Center. Axis Labs acquired licensing rights under the University’s worldwide patent portfolio directed to creatine ethyl ester as a nutritional supplement. The patented technology was developed at the University by faculty member Dr. Jonathan Vennerstrom, a Professor and the Interim Chair of Pharmaceutical Sciences at the University, and former faculty member Dr. Donald Miller, now an Associate Professor with the Department of Pharmacology & Therapeutics at the University of Manitoba.
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